老鼠-常州中科脂典生物技术有限责任公司

Mice (小鼠/大鼠）

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brain

brain (大脑）

brain/prefrontal cortex前额皮质

brain/cortical neurons 皮质神经元

brain/nigrostriatal 黑质纹状体

brain/caudal medulla oblongata尾髓延髓

brain/hippocampus海马区

brain/striatum纹状体

heart 心脏

livers 肝脏

lung 肺

plasma 血浆

sebaceous glands 皮脂腺

adipose 脂肪组织

embryonic fibroblasts 胚胎成纤维细胞

muscles 肌肉

mammary gland 乳腺

Lam S M, Wang R, Miao H, et al. An integrated method for direct interrogation of sphingolipid homeostasis in the heart and brain tissues of mice through postnatal development up to reproductive senescence[J]. Analytica Chimica Acta, 2018.
Chan R B, Oliveira T G, Cortes E P, et al. Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.[J]. Journal of Biological Chemistry, 2012, 287(4):2678-88.
Lim W L, Lam S M, Shui G, et al. Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice.[J]. Neurobiology of Aging, 2013, 34(9):2217-2224.
Long N N, Ma D, Shui G, et al. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid[J]. Nature, 2014, 509(7501):503.
Jenner A M, Lim W L F, Ng M P E, et al. The effect of APOE, genotype on brain levels of oxysterols in young and old human APOE, ε2, ε3 and ε4 knock-in mice[J]. Alzheimers & Dementia the Journal of the Alzheimers Association, 2010, 6(4):S255-S256.
Oliveira T G, Chan R B, Tian H, et al. Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits[J]. Journal of Neuroscience the Official Journal of the Society for Neuroscience, 2010, 30(49):16419-28.
Lee L H, Shui G, Farooqui A A, et al. Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids?[J]. Int J Neuropsychopharmacol, 2009, 12(7):953-964.
Sharman M J, Shui G, Fernandis A Z, et al. Profiling brain and plasma lipids in human APOE epsilon2, epsilon3, and epsilon4 knock-in mice using electrospray ionization mass spectrometry.[J]. Journal of Alzheimers Disease Jad, 2010, 20(20):105-11.

brain/cortical neurons

皮质神经元

brain/nigrostriatal

黑质纹状体

brain/caudal medulla oblongata

尾髓延髓

Ma M T, Yeo J F, Shui G, et al. Systems wide analyses of lipids in the brainstem during inflammatory orofacial pain - evidence of increased phospholipase A(2) activity.[J]. European Journal of Pain, 2012, 16(1):38-48.

brain/hippocampus

海马区

Lee H W, Tan C H, Lo Y L, et al. Brain lipid changes after repetitive transcranial magnetic stimulation: potential links to therapeutic effects?[J]. Metabolomics, 2012, 8(1):19-33.

brain/striatum

纹状体

Lee H W, Tan C H, Lo Y L, et al. Brain lipid changes after repetitive transcranial magnetic stimulation: potential links to therapeutic effects?[J]. Metabolomics, 2012, 8(1):19-33.

heart 心脏

livers 肝脏

lung 肺

plasma 血浆

sebaceous glands

皮脂腺

Zhang S, Shui G, Wang G, et al. Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands[J]. Molecular & Cellular Biology, 2014, 34(10):1827-1838.

adipose 脂肪组织

embryonic fibroblasts

胚胎成纤维细胞

muscles 肌肉

mammary gland

乳腺

Wang W, Lv N, Zhang S, et al. Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids[J]. Nature Medicine, 2012, 18(2):235.

Lim L, Jacksonlewis V, Wong L C, et al. Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease[J]. Cell Death & Differentiation, 2012, 19(3):416.

brain/prefrontal cortex

前额皮质

brain (大脑）

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