人类-常州中科脂典生物技术有限责任公司

Human 人类

plasma 血浆

Song JW#, Lam SM#, Fan X#, Cao WJ, Wang SY, Tian H, CHUA GH, Zhang C, Meng FP, Xu Z, Fu JL, Huang L, Xia P, Yang T, Zhang SH, Li BW, Jiang TJ, Wang RX, Wang ZH, Shi M, Zhang JY*, Wang FS*, Shui G*, Omics-driven systems interrogation of metabolic dysregulation in COVID-19 pathogenesis. Cell Metabolism 2020,
Chen, Yanxing, Lin, Caixiu, Guo, Zhangyu, Zhao, Shuai, Zhu, Yueli, Huang, Fude, Shui, Guanghou, Lam, Sin Man, Pu, Jiali, Yan, Yaping, Liu, Zhirong, Zhang, Baorong. Altered Expression Profile of Phosphatidylinositols in Erythrocytes of Alzheimer’s Disease and Amnestic Mild Cognitive Impairment Patients. Journal of Alzheimer'sDiseas. 2019, doi:10.3233
Lu J#, Lam SM#, Wan Q, Shi L, Huo Y, Chen L, Tang X, Li B, Wu X, Peng K, Li M, Wang S, Xu Y, Xu M, Bi Y, Ning G, Shui G*, Wang W*. High-Coverage Targeted Lipidomics Reveals Novel Serum Lipid Predictors and Lipid Pathway Dysregulation Antecedent to Type 2 Diabetes Onset in Normoglycemic Chinese Adults. Diabetes Care. DOI:10.2337/dc19-0100.
Chatterjee P, Lim W L, Shui G, et al. Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study[J]. Journal of Alzheimers Disease, 2016, 50(3):887-894.
Begum H, Li B, Shui G, et al. Discovering and validating between-subject variations in plasma lipids in healthy subjects[J]. Scientific Reports, 2016, 6:19139.
Shui G, Stebbins J W, Lam B D, et al. Comparative Plasma Lipidome between Human and Cynomolgus Monkey: Are Plasma Polar Lipids Good Biomarkers for Diabetic Monkeys?[J]. Plos One, 2011, 6(5):e19731.
Shui G, Lam S M, Stebbins J, et al. Polar lipid derangements in type 2 diabetes mellitus: potential pathological relevance of fatty acyl heterogeneity in sphingolipids[J]. Metabolomics, 2013, 9(4):786-799.
Chua C P, Shui G, Cazenavegassiot A, et al. Changes in Plasma Lipids during Exposure to Total Sleep Deprivation[J]. Sleep, 2015, 38(11).
Chua E C, Shui G, Lee I T, et al. Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans[J]. Pnas, 2013, 110(35):14468-14473.

tear 泪

brain/temporal cortex

颞叶皮质

Lam S M, Wang Y, Duan X, et al. Brain lipidomes of subcortical ischemic vascular dementia and mixed dementia[J]. Neurobiology of Aging, 2014, 35(10):2369-2381.

brain 脑

Chan R B, Oliveira T G, Cortes E P, et al. Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.[J]. Journal of Biological Chemistry, 2012, 287(4):2678-88.

brain/visual cortex

视觉皮层

Cheng D, Jenner A M, Shui G, et al. Lipid Pathway Alterations in Parkinson's Disease Primary Visual Cortex[J]. Plos One, 2011, 6(2):e17299.

auto-antigens and antibodies

自身抗原和抗体

Jovanović V, Abdul A N, Lim Y T, et al. Correction: Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus[J]. Plos One, 2013, 8(2):e55639.

Sebaceous Glands

皮脂腺

Zhang S, Shui G, Wang G, et al. Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands[J]. Molecular & Cellular Biology, 2014, 34(10):1827-1838.

sputum 痰

Shui G, Bendt A K, Jappar I A, et al. Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice[J]. Embo Molecular Medicine, 2012, 4(1):27-37.

Hela cells

Hela 细胞

Chen L, Ma MY, Sun M, Jiang LY, Zhao XT, Fang XX, Lam SM, Shui GH, Luo J, Shi XJ, Song BL. Endogenous sterol intermediates of the mevalonate pathway regulate HMG-CoA reductase degradation and SREBP-2 processing. J Lipid Res. 2019, doi: 10.1194/jlr.RA119000201.

Mesentery

肠系膜

Liu RQ, Qiao SH, Shen WS, Liu Y, Lu Y, Huang LY, Guo Z, Gong JF, Shui G, Li Y, Zhu WM*. Disturbance of Fatty Acid Desaturation Mediated by FADS2 in Mesenteric Adipocytes Contributes to Chronic Inflammation of Crohn’s Disease. J Crohns Colitis. DOI: 10.1093/ecco-jcc/jjaa086.

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